Creating a hole in a cylinder off center

[Radi]

Or:
1- create a cylinder
2 - select top or down cylinder face and use <Put On> command, then click on surface which you want a hole and right mouse click to continue
3- select all faces of cylinder except that one that is putted before and use <collapse>
4- last step. Select that cylinder face and surface below, and use bridge command.

Sorry, Im doing this in memory now, but should work . :-)
Write if you need something :-) always glad to help